Map All amino acids have two ionizable functional groups: an a-amino group (average pKa of 9.4) and an a-carboxylic acid group (average pKa of 2.2). Arginine also has an ionizable side chain (R group) with a pKa of -12.5. One of the possible ionization states of arginine is shown below. H3N CH-COH CH2 CH2 CH2 NH C NH2 NH2 At what pH would the above structure be the predominant ionization state? Note: Consider the ionization state of all three of the functional groups. pH Select answer Scroll down for more of this question. The protonated form of the R group of arginine is shown in the structure above. The ratio of the charged (protonated) form to the deprotonated form depends on the pKa of the R group and the pH of Previous Give Up & View Solution Check Answer NxtExt Hint At what pH would the above structure be the predominant ionization state? Note: Consider the ionization state of al three of the functional groups pHSelect answer Scroll down for more of this question. The protonated form of the R group of arginine is shown in the structure above. The ratio of the charged (protonated) form to the deprotonated form depends on the pka of the R group and the pH of the solution. Select all the pH values at which the charged form of the R group would predominate. 5.1 7.4 12.5 13.3 Previous & Give Up & View Solution Check Answer Next Exit nt