18 Aug Question: Huntington’s Disease Is A Fatal Syndrome Caused By A Mutation In The HD Gene. The Disease Has An Average Age Of Onset Of 35 And The Majority Of Individuals That Are Affected Are Heterozygotes. What Is The Probability That A 25 Year Old Woman With No Symptoms And Who Is The Daughter Of A Man That Has HD And A Mother Who Does Not Will Have A Child That …
Huntington’s Disease is a fatal syndrome caused by a mutation in the HD gene. The disease has an average age of onset of 35 and the majority of individuals that are affected are heterozygotes. What is the probability that a 25 year old woman with no symptoms and who is the daughter of a man that has HD and a mother who does not will have a child that will have the mutant HD allele?
A. 75% B. 50% C. 25% D. 100%
-I think the answer to this question is 25%, but i’m a bit confused. I know that the daughter’s chance of having HD is 50%, but when I do a Punnet square of her and an unaffected male I either get a 0% chance that her child will not have HD or a 50% that she will have the mutant allele. Can someone answer this question in detail?
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