25 Aug Bio Hw!
Consumer genomics has become a big business and has grown out of ancestry testing from private companies analyzing anyone’s genome for specific markers related to ancestry. Consumer genomics, however, offers genetic markers for clinical variants, i.e. known mutations (mostly SNPs) that are linked to diseases, susceptibility to drugs or infections. In 2013, the FDA sent a cease and desist letter to the biggest private consumer genomics company 23andMe (Links to an external site.)Links to an external site. and prohibited them from giving customers ‘medical advice’ (Links to an external site.)Links to an external site.. (Note: on April 6, 2017, the FDA reversed its ruling (Links to an external site.)Links to an external site. allowing 23andMe to proved consumer genetics). The company sequenced 100+ markers related to diseases and gave the customer a short explanation of the associated risk (e.g. Huntington’s disease, Alzheimer’s, obesity and diabetes, to name a few). It could continue its ancestry testing division. In July of 2018, the company announced that it will start a collaboration with GlaxoSmithKline (Links to an external site.)Links to an external site. (GSK) to accelerate their ability to make novel treatments and cures a reality based on the genetic data and health data provided by its costumer data base. 23andMe customer have the option to opt in or out of this deal with the pharmaceutical company. Discuss this rapidly changing approach on using consumer genetic data, which was based on the policy that only medically trained experts (e.g. your doctor) can do genetic counseling. Is 23andMe’s approach genetic counseling? Do you think you should have the right to obtain any sequence in your genome and decide on your own what to make of it?
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