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QUESTION 1 G-protein coupled receptors are targets for several psychiatric

QUESTION 1

  1. G-protein      coupled receptors are targets for several psychiatric medications. Given      what we know about these receptors, what is the ultimate result we will      see when one of them is activated in a way that would potentiate an      action?

  

 

A.

 

Intracellular activation of second messengers

 

 

B.

 

Protein phosphorylation

 

 

C.

 

Modification of gene expression

3.75 points   

QUESTION 2

  1. A      patient arrives in the ED via EMS having a grand mal seizure. The ED      physician instructs the RN to give 10 milligrams of Diazepam IV X1 dose      STAT. The patient’s seizure breaks within 2 minutes of the Diazepam being      administered. The mechanism by which this medication causes rapid      resolution of seizure activity is via which receptor type (effector      pathway/receptor subtype)?

  

 

A.

 

Slow effector pathways/G-protein coupled receptor

 

 

B.

 

Slow effector pathway/ion channel

 

 

C.

 

Rapid effector pathways/G-protein coupled receptor

 

 

D.

 

Rapid effector pathway/ion channel

3.75 points   

QUESTION 3

  1. The      synaptic cleft is best characterized by which of the following statements?

  

 

A.

 

The synaptic cleft is the space between a single neuron’s   dendrites and axon terminals in which intracellular communication occurs   through the release of neurotransmitters allowing for signal conduction   throughout the central nervous system.

 

 

B.

 

The synaptic cleft is the space between the cell body and   axon terminals that allows for release of neurotransmitters from the   presynaptic neuron for intercellular communication with an adjacent neuron   (post synaptic neuron).

 

 

C.

 

The synaptic cleft is an area where dendrites and axon   terminals are within close proximity, allowing for the release of a   neurotransmitter from a presynaptic neuron that can interact with receptors   on dendritic cells of a post synaptic neuron, which is the main basis for   intercellular communication of neurons.

3.75 points   

QUESTION 4

  1. Which      neurotransmitter is considered the major excitatory neurotransmitter?

  

 

A.

 

Glycine

 

 

B.

 

GABA

 

 

C.

 

Glutamate

 

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